WASHINGTON (AP) — The Supreme Court has rejected an emergency appeal from health care workers in Maine to block a vaccine mandate that went into effect Friday.

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Three conservative justices noted their dissents.

The state is not offering a religious exemption to hospital and nursing home workers who risk losing their jobs if they are not vaccinated.

Only New York and Rhode Island also have vaccine mandates for health care workers that lack religious exemptions.

Both are the subject of court fights and a court has allowed workers in New York to seek religious exemptions while the lawsuit plays out.

Answers to 25 common COVID-19 vaccine questions

Vaccinations for COVID-19 began being administered in the U.S. on Dec. 14, 2020. The quick rollout came a little more than a year after the virus was first identified in November 2019. The impressive speed with which vaccines were developed has also left a lot of people with a lot of questions. The questions range from the practical—how will I get vaccinated?—to the scientific—how do these vaccines even work?

Keep reading to discover answers to 25 common COVID-19 vaccine questions.