WASHINGTON (AP) — President Joe Biden has announced sweeping new federal vaccine requirements affecting as many as 100 million Americans in an all-out effort to increase COVID-19 vaccinations and curb the surging delta variant.

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The government's expansive new rules, announced Thursday, mandate that all employers with more than 100 workers require them to be vaccinated or test for the virus weekly, affecting about 80 million Americans.

Biden is also signing an executive order requiring vaccination for all employees of the executive branch and contractors who do business with the federal government.

No testing opt-out is expected to be included for the executive branch requirement.

LOOK: Answers to 30 common COVID-19 vaccine questions

While much is still unknown about the coronavirus and the future, what is known is that the currently available vaccines have gone through all three trial phases and are safe and effective. It will be necessary for as many Americans as possible to be vaccinated in order to finally return to some level of pre-pandemic normalcy, and hopefully these 30 answers provided here will help readers get vaccinated as soon they are able.